Question: Dear Dr. Lawton,
I had 2 pathologists look at my surgical pathology. It seems that they both saw the same thing, but disagreed on how to call it.
One pathologist called it invasive mammary carcinoma with lobular features, the other called it IDC with single file growth pattern. My single focal tumor showed single file [...]
Question: Can you help me understand this report?
Breast Right, biospy:
Infiltrating ductal carcinoma
SBR/Nottingham grade 2/3
Tubular score 2.
Nuclear score 2.
Mitotic score 2 (focal).
No evidence of angiolymphatic invasion
Cancerization og lobules
Ductal carcinoma in situ
Solid, papillary and cribriform patterns
Nuclear grade 2-3
Comedonecrosis present
Microcalcifications associated with in situ malignancy
Immunostains -
Estrogen receptor – diffuse strong positivity in 97% of tumor cell nuclei
Progesterone receptor [...]
Question: Pathologist gave a diagnosis of Invasive ductal cancer grade 1 (2/2/1), however when asked said it was a tubular cancer are these two different? thank you
Question: What is the difference between invasive lobular and ductal carcinoma? My first biopsy I had at my ultrasound said “invasive lobular carcinoma grade 2/3″ and my surgery biopsy said “invasive ductal carcinoma grade 2/3″. Does this make any difference?
The newest edition of the AJCC’s Staging Manual is out and there are some changes to breast cancer staging which took effect January 1, 2010. Several updates in the new edition I felt were good include:
- Moving T0/T1 tumors with only micrometases in the axillary nodes to stage IB from the IIA category.
- Re-affirming the [...]
Knowing the stage of your breast cancer helps your medical team determine how big the cancer is and if it has spread. This helps them guide your therapy and provide reliable prognostic information.
In general, staging is done following your surgery, either after lumpectomy or mastectomy. It usually includes evaluation of the lymph nodes in your [...]
Question: My lumpectomy report says: Invasive ductal carcinoma, two foci, 2.4 cm, combined histologic grade II/III, margins widely free (>5mm), see comment. The comment says there were two tumors, one 1.3 cm and one 0.6 cm, total span 2.4 cm. My question is–my doctor has staged me as IIA (my nodes were negative)–but my [...]
Question: I am confused about my cancer stage as it seems much worse than when I originally had my surgery. Based on the report I asked for, my cancer is an invasive lobular carcinoma and measures 1.3 cm. I had a lumpectomy and sentinel node biopsy; my node was negative. My cancer is ER and [...]
Question: My report says “in situ and invasive ductal carcinoma, intermediate grade, 2.4 cm, margins clear” and my lymph node was negative; the cancer is ER positive (80%), PR positive (60%), HER2 negative. My surgeon said I don’t need more surgery but I need to see an oncologist to discuss chemotherapy. I am [...]
Question: My daughter was diagnosed w/trip neg breast cancer two years ago…She was 58, Caucasian, postmenapausal, no family history, on statins and an anti-depressant…Her only known risk factor was being extremely overweight (200+lb)…She had a lumpectomy…Her tumor was large but nodes were clear…she was treated with max chemo and radiation…her case is singular compared to [...]