Question: In 2006, I had lumpectomy and radiation in right breast following diagnosis of DCIS. I was 38. No family history. First mammogram. Margins were clear. I have had MRIs every six months alternating with mammograms every six months. Two weeks ago, I had a stereotatic biopsy that indicated ADH in the left breast [...]
Question: I looked for a way to post on your ask the pathologists forum but was unable so here is my question. I noticed a lump a few months ago and saw my primary care MD, sent for a mammagrom and US. Mammagram totally normal, no calcifications, US saw the mass and a biospy was [...]
A recent news release from Genomic Health, Inc. indicates preliminary data shows that the Oncotype DX® test can provide a score predicting risk of local recurrence in patients with a diagnosis of ductal carcinoma in situ (DCIS).
DCIS is a very heterogeneous disease and there is disagreement in the breast care community as to how to [...]
Question: Hello, and thanks for taking the time to answer my questions.
March 29th first biopsy done, clinical information and history: Bloody nipple discharge left breast for 20 months, papilloma suspected, mammogram clear. Diagnosis after excision: 1. Low grade DCIS 2. Focal proliferative fibrocystic changes and small intraductal papilloma 3. DCIS [...]
Question: I am 40 years old and had my first mammogram 2 months ago. It showed a 5 mm area of micro calcifications. I had a stereotactic vacuum assisted biopsy and 8 samples were retrieved. The histopath came back as DCIS – cribriform, clinging, with a nuclear grade of 2 out of 3. The slides [...]
I recently gave a talk on second opinions in breast pathology at the 21st Annual Conference of the National Consortium of Breast Centers in Las Vegas. A modified version of that talk is available here as a pdf:
Second_Opinion_Pathology
The first part of the talk covers some of the data in the literature and the second part [...]
In a recent issue of the journal Cancer there are two interesting articles looking at two types of radiation therapies vs. no radiation for a subset of patients with DCIS.
This has long been a controversy amongst breast care specialists. Does all DCIS following lumpectomy need to be treated by radiation? Or is there a subset [...]
If you haven’t seen this recent article from the New York Times it’s worth a read.
I have posted before about the importance of getting your breast biopsy diagnosed from a pathologist who specializes in breast pathology. This article points out how subtle the distinction can be between atypical ductal hyperplasia and low grade ductal carcinoma [...]
Question: I recently had a breast biopsy with invasive ductal carcinoma, grade 3 and ductal carcinoma in situ. My report said “the carcinoma is estrogen and progesterone receptor negative (<5%) and negative for her2/neu over-expression (1+).” I read online that sometimes even less than 5% could still be positive for the estrogen receptor. [...]
Question: Hi I Had a sterotatic biopsy that revealed On the pathology report that I picked up said A. Columnar cell lesion with focal microcalcifications B. Lobular carcinoma in situ. I am so confused My doctor said I have DCIS but its lobular. Treatment plan is lumpectomy and lymph node aspiration and then 5 years of [...]