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	<title>Pacific Breast Pathology &#187; invasive carcinoma</title>
	<atom:link href="http://www.pacificbreastpathology.com/blog/tag/invasive-carcinoma/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.pacificbreastpathology.com/blog</link>
	<description>Pacific Breast Pathology weblog</description>
	<lastBuildDate>Fri, 16 Dec 2011 21:08:18 +0000</lastBuildDate>
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			<item>
		<title>Recurrent Breast Cancer with No Residual Cancer Found at Mastectomy</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/998/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/998/#comments</comments>
		<pubDate>Thu, 15 Dec 2011 20:50:11 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[core biopsy]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[invasive ductal carcinoma]]></category>

		<guid isPermaLink="false">http://www.pacificbreastpathology.com/blog/?p=998</guid>
		<description><![CDATA[Question:  Hi. I had a reoccurrence with my breast cancer in may of this year, they did a punch biopsy on it and it came back as IDC grade 2, ER and PR positive.  On the punch biopsy pathology report there are no notes on margins it just says Recurrent IDC is multifocal and surrounding [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/998/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Terminology of Invasive Mammary Carcinoma</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/969/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/969/#comments</comments>
		<pubDate>Mon, 14 Nov 2011 00:29:52 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[breast cancer stage]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[invasive ductal carcinoma]]></category>
		<category><![CDATA[invasive lobular carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[stage]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=969</guid>
		<description><![CDATA[Question: Dear Dr. Lawton,
I had 2 pathologists look at my surgical pathology. It seems that they both saw the same thing, but disagreed on how to call it.
One pathologist called it invasive mammary carcinoma with lobular features, the other called it IDC with single file growth pattern.  My single focal tumor showed single file [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/969/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Understanding Pathology Results</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/understanding-pathology-results/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/understanding-pathology-results/#comments</comments>
		<pubDate>Tue, 11 Oct 2011 15:25:02 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[breast cancer stage]]></category>
		<category><![CDATA[carcinoma in situ]]></category>
		<category><![CDATA[chemotherapy]]></category>
		<category><![CDATA[core biopsy]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[HER2]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[treatment]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=943</guid>
		<description><![CDATA[Question:  Can you help me understand this report?
Breast Right, biospy:
Infiltrating ductal carcinoma
SBR/Nottingham grade 2/3
Tubular score 2.
Nuclear score 2.
Mitotic score 2 (focal).
No evidence of angiolymphatic invasion
Cancerization og lobules
Ductal carcinoma in situ
Solid, papillary and cribriform patterns
Nuclear grade 2-3
Comedonecrosis present
Microcalcifications associated with in situ malignancy
Immunostains -
Estrogen receptor &#8211; diffuse strong positivity in 97% of tumor cell nuclei
Progesterone receptor [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/understanding-pathology-results/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Pacific Breast Pathology</title>
		<link>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/pacific-breast-pathology/</link>
		<comments>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/pacific-breast-pathology/#comments</comments>
		<pubDate>Wed, 05 Oct 2011 18:12:22 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[PBP Blog]]></category>
		<category><![CDATA[PBP News]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[core biopsy]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[second opinion]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=936</guid>
		<description><![CDATA[Seattle Breast Pathology Consultants has joined forces with another breast pathologist to form Pacific Breast Pathology.  In addition to our existing second opinion consultation service, we will now be providing services to radiologists and surgeons for primary diagnostic interpretation of breast core biopsies and surgical specimens performed in California.  We also will have full service [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/pacific-breast-pathology/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Tubular Carcinoma</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tubular-carcinoma-2/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tubular-carcinoma-2/#comments</comments>
		<pubDate>Mon, 05 Sep 2011 00:46:45 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[immunohistochemistry]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[invasive ductal carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[second opinion]]></category>
		<category><![CDATA[treatment]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=927</guid>
		<description><![CDATA[Question:  Hello: I am a 50 year old premenopausal female. I had a 2.5 mm tubular carcinoma diagnosed in Dec 2010 and had a simple mastectomy and neg SNB. I then had a prophylactic mastectomy in March of the other side. There were atypical hyperplastic lobular and ductal cell changes in the remainder of [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tubular-carcinoma-2/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>History of DCIS in One Breast, Now ADH in the Opposite Breast</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/history-of-dcis-in-one-breast-now-adh-in-the-opposite-breast/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/history-of-dcis-in-one-breast-now-adh-in-the-opposite-breast/#comments</comments>
		<pubDate>Thu, 25 Aug 2011 15:37:05 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[atypical ductal hyperplasia]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[carcinoma in situ]]></category>
		<category><![CDATA[core biopsy]]></category>
		<category><![CDATA[ductal carcinoma in situ]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[radiation]]></category>
		<category><![CDATA[surgical margins]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=923</guid>
		<description><![CDATA[Question:  In 2006, I had lumpectomy and radiation in right breast following diagnosis of DCIS.  I was 38.  No family history.  First mammogram.  Margins were clear.  I have had MRIs every six months alternating with mammograms every six months.  Two weeks ago, I had a stereotatic biopsy that indicated ADH in the left breast [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/history-of-dcis-in-one-breast-now-adh-in-the-opposite-breast/feed/</wfw:commentRss>
		<slash:comments>1</slash:comments>
		</item>
		<item>
		<title>Tubular Carcinoma</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tubular-carcinoma/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tubular-carcinoma/#comments</comments>
		<pubDate>Fri, 22 Jul 2011 17:20:35 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[breast cancer stage]]></category>
		<category><![CDATA[cancer grade]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[HER2]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[invasive ductal carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[stage]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=895</guid>
		<description><![CDATA[Question:  Pathologist gave a diagnosis of Invasive ductal cancer grade 1 (2/2/1), however when asked said it was a tubular cancer are these two different? thank you
 Answer: Tubular carcinomas are a special type of invasive carcinoma that is in a group often called &#8220;favorable&#8221; prognosis breast cancers. Recent data has confirmed this. Grade [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tubular-carcinoma/feed/</wfw:commentRss>
		<slash:comments>2</slash:comments>
		</item>
		<item>
		<title>Invasive Lobular vs. Invasive Ductal Carcinoma</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/invasive-lobular-vs-invasive-ductal-carcinoma/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/invasive-lobular-vs-invasive-ductal-carcinoma/#comments</comments>
		<pubDate>Sun, 19 Jun 2011 22:56:46 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[breast cancer stage]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[HER2]]></category>
		<category><![CDATA[immunohistochemistry]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[invasive ductal carcinoma]]></category>
		<category><![CDATA[invasive lobular carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=890</guid>
		<description><![CDATA[Question:  What is the difference between invasive lobular and ductal carcinoma? My first biopsy I had at my ultrasound said &#8220;invasive lobular carcinoma grade 2/3&#8243; and my surgery biopsy said &#8220;invasive ductal carcinoma grade 2/3&#8243;. Does this make any difference?
 Answer: Not really, because a core biopsy only samples part of the tumor.  [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/invasive-lobular-vs-invasive-ductal-carcinoma/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Tumor Grade Changed from 1 to 3</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tumor-grade-changed-from-1-to-3/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tumor-grade-changed-from-1-to-3/#comments</comments>
		<pubDate>Sun, 19 Jun 2011 16:23:06 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[cancer grade]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=885</guid>
		<description><![CDATA[Question: My core biopsy path report stated a tumor grade of 1. Four weeks later, the lumpectomy path report states tumor grade 3.  Can the tumor really be progressing this rapidly? Thanks for your time.
 Answer: It doesn&#8217;t necessarily mean it is progressing that fast.   Did the same pathologist read both biopsies? [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/tumor-grade-changed-from-1-to-3/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>DCIS and Need for Re-Excision Following Positive Margins</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/845/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/845/#comments</comments>
		<pubDate>Tue, 10 May 2011 18:02:00 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[atypical ductal hyperplasia]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[carcinoma in situ]]></category>
		<category><![CDATA[ductal carcinoma in situ]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[papilloma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[second opinion]]></category>
		<category><![CDATA[surgical margins]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=845</guid>
		<description><![CDATA[Question: Hello, and thanks for taking the time to answer my questions.
March 29th first biopsy done, clinical information and history: Bloody  nipple discharge left breast for 20 months, papilloma suspected,  mammogram clear.  Diagnosis after excision: 1. Low grade DCIS 2. Focal  proliferative fibrocystic changes and small intraductal papilloma 3.  DCIS [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/845/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Lobular Neoplasia Talk Now Posted</title>
		<link>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/lobular-neoplasia-talk-now-posted/</link>
		<comments>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/lobular-neoplasia-talk-now-posted/#comments</comments>
		<pubDate>Fri, 25 Mar 2011 18:33:33 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[PBP Blog]]></category>
		<category><![CDATA[atypical lobular hyperplasia]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[lobular carcinoma in situ]]></category>
		<category><![CDATA[pathologist]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=772</guid>
		<description><![CDATA[I recently gave a talk in Mexico City on lobular neoplasia (alh/lcis) which is now available here as a pdf:
Lobular_neoplasia
The talk covers the difference between ALH and LCIS and the new variants of LCIS such as pleomorphic LCIS and LCIS with necrosis. We also talk about the possibility that LCIS is a precursor to invasive [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/lobular-neoplasia-talk-now-posted/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Second Opinion Pathology Talk</title>
		<link>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/second-opinion-pathology-talk/</link>
		<comments>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/second-opinion-pathology-talk/#comments</comments>
		<pubDate>Thu, 24 Mar 2011 17:22:44 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[PBP Blog]]></category>
		<category><![CDATA[atypical ductal hyperplasia]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[carcinoma in situ]]></category>
		<category><![CDATA[ductal carcinoma in situ]]></category>
		<category><![CDATA[immunohistochemistry]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[invasive lobular carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>
		<category><![CDATA[second opinion]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=763</guid>
		<description><![CDATA[I recently gave a talk on second opinions in breast pathology at the 21st Annual Conference of the National Consortium of Breast Centers in Las Vegas. A modified version of that talk is available here as a pdf:
Second_Opinion_Pathology
The first part of the talk covers some of the data in the literature and the second part [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/second-opinion-pathology-talk/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Prognostic Marker Changes in Metastatic Breast Cancer</title>
		<link>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/prognostic-marker-changes-in-metastatic-breast-cancer/</link>
		<comments>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/prognostic-marker-changes-in-metastatic-breast-cancer/#comments</comments>
		<pubDate>Mon, 04 Oct 2010 19:54:40 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[PBP Blog]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[HER2]]></category>
		<category><![CDATA[immunohistochemistry]]></category>
		<category><![CDATA[invasive carcinoma]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=705</guid>
		<description><![CDATA[There is a recent study published in the September 23 issue of Breast Cancer Research that looked at changes in prognostic markers (estrogen/progesterone receptor and HER2/neu) between primary breast cancers and metastatic lesions. If you click on the Breast Cancer Research link it will provide you with the abstract.  The full article is temporarily free from [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/dr_lawtons_blog/prognostic-marker-changes-in-metastatic-breast-cancer/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Can Breast Cancer Be Diagnosed On a Bone Marrow Biopsy?</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/can-breast-cancer-be-diagnosed-on-a-bone-marrow-biopsy/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/can-breast-cancer-be-diagnosed-on-a-bone-marrow-biopsy/#comments</comments>
		<pubDate>Thu, 05 Aug 2010 17:13:44 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[immunohistochemistry]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=698</guid>
		<description><![CDATA[Question: My 75 y/o mother who was sent to an oncologist due to a bone scan that showed a hot spot on the right rib. A bone marrow biopsy/aspir was done and she was diagnosed with breast cancer with mets to the spine-results were ER/PR +.  Mammograms, cat scans, Petscans were neg.  She [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/can-breast-cancer-be-diagnosed-on-a-bone-marrow-biopsy/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Estrogen Receptor Staining in Breast Cancer</title>
		<link>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/estrogen-receptor-staining-in-breast-cancer/</link>
		<comments>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/estrogen-receptor-staining-in-breast-cancer/#comments</comments>
		<pubDate>Tue, 29 Jun 2010 00:23:55 +0000</pubDate>
		<dc:creator>drlawton</dc:creator>
				<category><![CDATA[Ask the Pathologist]]></category>
		<category><![CDATA[breast cancer]]></category>
		<category><![CDATA[ductal carcinoma in situ]]></category>
		<category><![CDATA[estrogen receptor]]></category>
		<category><![CDATA[HER2]]></category>
		<category><![CDATA[invasive carcinoma]]></category>
		<category><![CDATA[pathologist]]></category>

		<guid isPermaLink="false">http://www.breastpathologyconsults.com/blog/?p=681</guid>
		<description><![CDATA[Question: I recently had a breast biopsy with invasive ductal carcinoma, grade 3 and ductal carcinoma in situ.  My report said &#8220;the carcinoma is estrogen and progesterone receptor negative (&#60;5%) and negative for her2/neu over-expression (1+).&#8221;  I read online that sometimes even less than 5% could still be positive for the estrogen receptor. [...]]]></description>
		<wfw:commentRss>http://www.pacificbreastpathology.com/blog/ask_the_pathologist/estrogen-receptor-staining-in-breast-cancer/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
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